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Because the metabolic profile may be an important determinant of bioactivity after soy intake, we studied the serum and urine isoflavone concentrations in 3 animal models and compared them. In this study, additional data on the distribution of isoflavones in serum and/or tissues of rats and pigs fed dietary isoflavones were generated. In the present study, we characterized the metabolic phenotype of isoflavones in female rats, monkeys, pigs, and women after consumption of diets containing soy protein isolate.
In the present study, bone turnover parameters were examined among workers at a local hospital whose isoflavone aglycone supplementation was different Metabolic phenotype of isoflavones differ among female rats, pigs, monkeys, and women.(q51810532) Daily genistein, daidzein, and glycitein intake (mg/kg body weight) was estimated to be 13.0, 9.9, and 2.4, respectively, for rats
4.8, 3.7, and 0.8, respectively, for monkeys
Clarkson, et al., “metabolic phenotypes of isoflavones differ among female rats, pigs, monkeys, and women,” journal of. Metabolic phenotype of isoflavones differ among female rats, pigs, monkeys, and women Thus, there were significant interspecies differences in isoflavone metabolism, and the overall metabolic profile of pigs was closer to that of women than that of rats or monkeys.
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